Disease: Ischemic stroke ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.030 Biomarker disease BEFREE Using a transgenic mouse model of ischemic stroke we checked for a possible interaction of antiphospholipid antibodies (aPL) which often cause thromboses as well as central nervous system (CNS) involvement under non-thrombotic conditions and the TWEAK/Fn14 pathway known to be adversely involved in inflammatory and ischemic brain disease. 20557950 2010
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.030 Biomarker disease BEFREE Induction of the cytokine TWEAK and its receptor Fn14 in ischemic stroke. 18793781 2008
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.030 Biomarker disease BEFREE In addition, inhibition of TWEAK activity by either treatment with a Fn14-Fc fusion protein or neutralizing anti-TWEAK antibodies has shown therapeutic efficacy in animal models of ischemic stroke, cerebral edema, and multiple sclerosis. 17917114 2007