PDE1C, phosphodiesterase 1C, 5137

N. diseases: 41; N. variants: 57
Disease: melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma 		0.020 GeneticVariation disease BEFREE The SNPs rs215605 in the PDE1C gene and rs6265 in the BDNF gene significantly interacted with smoking status on melanoma risk (interaction P = 0.005 and P = 0.003 respectively). 27344179 2016
CUI: C0025202
Disease: melanoma
melanoma 		0.020 AlteredExpression disease BEFREE PDE1C mRNA is expressed and may play an important role in human malignant melanoma MAA cells. 19414353 2009