|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Synthesis, Characterization, and Inducing Tumor Cell Apoptosis of Two Ru(II) Complexes Containing Guanidinium as Ligands.
|
28425859 |
2018 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Selective Ru(II)/lawsone complexes inhibiting tumor cell growth by apoptosis.
|
28865744 |
2017 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Moreover, the silence of DCDC2 could rescue tumor suppression role of downregulated miR-645 on breast cancer metastasis.
|
29028086 |
2017 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The findings suggest that Ru(II)-CNEB is able to activate oxidative stress-apoptosis pathway via p53 (a tumor supressor protein) mediated repression of iPFK2, a key glycolytic regulator, in the DL cells in vivo.
|
25576833 |
2015 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
In this study, we have characterized a panel of NSC lung cancer cell lines for the expression of coiled-coil-domain containing 6 (CCDC6), a tumor suppressor gene involved in apoptosis and DNA damage response.
|
25302833 |
2015 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
A surgical specimen obtained from a 68-year-old female HCC patient was analyzed by triple combination array, which identified doublecortin domain-containing 2 (DCDC2) as a candidate tumor suppressor gene of HCC.
|
24034596 |
2013 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The fact that NSC 23175 protected p53(+/+) cells implicates a putative protective effect of the compound during radiotherapy of p53-mutated tumors.
|
23382585 |
2013 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
These findings may be relevant for the clinical management of prostate cancer as DCDC2 may signal tumors more prone to relapse and resistant to taxol treatment.
|
22733135 |
2013 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Third, we explored the effect of NSC-124854 on TMZ-induced in vivo tumor growth inhibition of MMR-deficient and MMR-proficient colonic xenografts implanted in female homozygous SCID mice.
|
21311763 |
2011 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
The addition of bortezomib further enhanced the efficacy of NSCs-TRAIL treated group in one of examined tumor models.
|
21802840 |
2011 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
These mutations convert the NSC or NPC to a BTSC, which then initiates and sustains the growth of the tumor.
|
19856100 |
2009 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
However, the molecular mechanisms of NSC targeting to hypoxic tumor areas are not well understood.
|
19074827 |
2008 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Daphnane-type diterpene gnidimacrin (NSC 252940) shows significant antitumor activity against murine tumors and human tumor cell lines.
|
12740906 |
2003 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
2, 5-bis(5-Hydroxymethyl-2-thienyl)furan (NSC 652287), is a representative of a series of thiophene derivatives that exhibit potent and selective antitumor activity against several tumor cell lines in the National Cancer Institute Anticancer Drug Screen.
|
10462535 |
1999 |