DCDC2, doublecortin domain containing 2, 51473

N. diseases: 128; N. variants: 23
Disease: Developmental reading disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0920296
Disease: Developmental reading disorder
Developmental reading disorder 		0.100 Biomarker disease BEFREE These include DCDC2, which has repeatedly been associated with developmental dyslexia in various European and American populations. 28400808 2017
CUI: C0920296
Disease: Developmental reading disorder
Developmental reading disorder 		0.100 GeneticVariation disease BEFREE Dyslexia is a reading disorder with strong associations with KIAA0319 and DCDC2. 28182973 2017
CUI: C0920296
Disease: Developmental reading disorder
Developmental reading disorder 		0.100 GeneticVariation disease BEFREE Polymorphisms in DCDC2 and S100B associate with developmental dyslexia. 25877001 2015
CUI: C0920296
Disease: Developmental reading disorder
Developmental reading disorder 		0.100 GeneticVariation disease BEFREE A deletion in intron 2 of the DCDC2 gene (hereafter DCDC2d) increases the risk for DD and related phenotypes. 25270309 2015
CUI: C0920296
Disease: Developmental reading disorder
Developmental reading disorder 		0.100 Biomarker disease BEFREE Thus, the association of DCDC2 and KIAA0319 with DD in Chinese population should be further validated and their contribution to DD etiology and pathology should be interpreted with caution. 25230923 2014
CUI: C0920296
Disease: Developmental reading disorder
Developmental reading disorder 		0.100 GeneticVariation disease BEFREE The DCDC2/intron 2 deletion and white matter disorganization: focus on developmental dyslexia. 24926531 2014
CUI: C0920296
Disease: Developmental reading disorder
Developmental reading disorder 		0.100 GeneticVariation disease BEFREE Our study demonstrated the association of DD with SNP rs4504469 of KIAA0319 and not with any SNPs of DCDC2. 23677054 2013
CUI: C0920296
Disease: Developmental reading disorder
Developmental reading disorder 		0.100 Biomarker disease BEFREE More specifically, our data support the view that DCDC2 influences both reading and memory impairments thus shedding further light into the etiologic basis and the phenotypic complexity of developmental dyslexia. 21881542 2012
CUI: C0920296
Disease: Developmental reading disorder
Developmental reading disorder 		0.100 Biomarker disease BEFREE The DCDC2 gene may not be a susceptibility factor for developmental dyslexia among the Han Chinese. 22490485 2012
CUI: C0920296
Disease: Developmental reading disorder
Developmental reading disorder 		0.100 GeneticVariation disease BEFREE Studies in different populations have established associations between DD and single nucleotide polymorphisms (SNPs) in a number of candidate genes, including DYX1C1, KIAA0319 and DCDC2. 21203818 2011
CUI: C0920296
Disease: Developmental reading disorder
Developmental reading disorder 		0.100 Biomarker disease BEFREE Both DCDC2 and DYX1C1 DD susceptibility genes appear to have a pleiotropic role on mathematics but not language phenotypes. 21046216 2011
CUI: C0920296
Disease: Developmental reading disorder
Developmental reading disorder 		0.100 Biomarker disease BEFREE This study provides support for DCDC2 as a risk gene for reading disorder, and suggests that this risk factor acts on normally varying reading skill in the general population. 20068590 2010
CUI: C0920296
Disease: Developmental reading disorder
Developmental reading disorder 		0.100 GeneticVariation disease BEFREE Variants within DCDC2 have shown association with DD in a US and a German sample. 17033633 2006