GSKIP, GSK3B interacting protein, 51527

N. diseases: 6; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023466
Disease: Leukemia, Monocytic, Chronic
Leukemia, Monocytic, Chronic 		0.300 Biomarker disease CTD_human Germline duplication of ATG2B and GSKIP predisposes to familial myeloid malignancies. 26280900 2015
CUI: C0023470
Disease: Myeloid Leukemia
Myeloid Leukemia 		0.300 Biomarker disease CTD_human Germline duplication of ATG2B and GSKIP predisposes to familial myeloid malignancies. 26280900 2015
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease 		0.300 Biomarker group CTD_human Germline duplication of ATG2B and GSKIP predisposes to familial myeloid malignancies. 26280900 2015
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.010 Biomarker disease BEFREE This study is the first to demonstrate a transient increase in phosphor-Tau caused by PKA, but not GSK3β, in the CSF and induced pluripotent stem cells (iPSCs) of AD, implying that both GSKIP and GSK3β function as anchoring proteins to strengthen the cAMP/PKA/Tau axis signaling during AD pathogenesis. 31640277 2019
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.010 PosttranslationalModification disease BEFREE It was found that HANR bind to GSKIP for regulating the phosphorylation of GSK3β in HCC. 29055955 2017
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.010 Biomarker group BEFREE Germline duplication of ATG2B and GSKIP predisposes to familial myeloid malignancies. 26280900 2015