SCLY, selenocysteine lyase, 51540

N. diseases: 161; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0086132
Disease: Depressive Symptoms
Depressive Symptoms
0.100 GeneticVariation phenotype BEFREE Depressive symptoms were assessed with the Symptom Checklist-25 (SCL-25) on both occasions. 31846899 2020
CUI: C0086132
Disease: Depressive Symptoms
Depressive Symptoms
0.100 GeneticVariation phenotype BEFREE The overall psychopathological burden, as measured by the SCL-90 Global Severity Index (GSI), significantly decreased during the study period (Z = -2.689; p = 0.007), with a relevant improvement with regards to depressive symptoms, anhedonia, and anxiety. 31543838 2019
CUI: C0086132
Disease: Depressive Symptoms
Depressive Symptoms
0.100 Biomarker phenotype BEFREE A device for self-monitoring of the mood state (MoMo) and validated scales such as the Profile of Mood States questionnaire (POMS), the Self-Report Symptom Inventory-Revised (SCL-90-R) and the Hamilton Depression Rating Scale (HDRS) were used to evaluate depressive symptoms. 30423466 2019
CUI: C0086132
Disease: Depressive Symptoms
Depressive Symptoms
0.100 Biomarker phenotype BEFREE We used voxel-based morphometry on a multicenter data set of 409 healthy nonclinical subjects to test the hypothesis that local hippocampal volume would be inversely correlated with subclinical depressive symptoms [Symptom Checklist 90-Revised (SCL-90-R) depression scores]. 31354542 2019
CUI: C0086132
Disease: Depressive Symptoms
Depressive Symptoms
0.100 GeneticVariation phenotype BEFREE The co-primary outcome measures were BMI and 20-item Depression Symptom Checklist (SCL-20) scores (range, 0 [best] to 4 [worst]) at 12 months. 30835308 2019
CUI: C0086132
Disease: Depressive Symptoms
Depressive Symptoms
0.100 Biomarker phenotype BEFREE Course of depression symptoms between 3 and 8 months after delivery using two screening tools (EPDS and HSCL-10) on a sample of Sudanese women in Khartoum state. 30089466 2018
CUI: C0086132
Disease: Depressive Symptoms
Depressive Symptoms
0.100 Biomarker phenotype BEFREE When looking at the total population, there was a significant correlation between TNF-α and both the HADS depressive symptoms and the SCL-90-R cluster somatisation. 30063870 2018
CUI: C0086132
Disease: Depressive Symptoms
Depressive Symptoms
0.100 GeneticVariation phenotype BEFREE Severity of mental distress and symptoms of depression were measured with the Symptom Checklist-90-Revised (SCL-90-R) and the Beck Depression Inventory (BDI), respectively. 30142462 2018
CUI: C0086132
Disease: Depressive Symptoms
Depressive Symptoms
0.100 AlteredExpression phenotype BEFREE Secondary outcomes include depression symptoms (BDI-II) after 15 months, anxiety symptoms (Beck's Anxiety Inventory (BAI)), level of functioning (Global Assessment of Function (GAF)) and psychological stress (Symptom Checklist-90-Revised (SCL-90-R)). 28732523 2017
CUI: C0086132
Disease: Depressive Symptoms
Depressive Symptoms
0.100 Biomarker phenotype BEFREE Severity of depression symptoms at baseline (subscale of the SCL-90-R questionnaire) significantly predicted membership of classes 2 and 3 vs class 1. 27787619 2017
CUI: C0086132
Disease: Depressive Symptoms
Depressive Symptoms
0.100 GeneticVariation phenotype BEFREE 104 participants [27 seronegative (SN)-non-Smokers, 26 SN-Smokers, 29 HIV+ non-Smokers, 22 HIV+ Smokers] were assessed for psychopathology symptoms (Symptom Checklist-90, SCL-90), depressive symptoms (Center for Epidemiologic Studies-Depression Scale, CES-D), impulsivity (Barratt Impulsiveness Scale, BIS), decision-making (The Iowa Gambling Task, IGT, and Wisconsin Card Sorting Test, WCST), and cognition (seven neurocognitive domains). 28303534 2017
CUI: C0086132
Disease: Depressive Symptoms
Depressive Symptoms
0.100 Biomarker phenotype BEFREE Episodic memory was significantly associated with follow-up SCL-90 depressive symptoms. 19133876 2009
CUI: C0086132
Disease: Depressive Symptoms
Depressive Symptoms
0.100 GeneticVariation phenotype BEFREE Anxiety and depression symptom scores from the SCL-90 questionnaire were observed in a large sample of nuclear families, and the effects of genes or family environment were estimated. 1827639 1991