SIRT7, sirtuin 7, 51547

N. diseases: 80; N. variants: 0
Disease: Colorectal Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.030 Biomarker disease BEFREE Thus, the data of the present study indicated a novel mechanistic role for Sirt7 as an oncogene in CRC malignancy, and Sirt7 may be a potential therapeutic target. 29467843 2018
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.030 Biomarker disease BEFREE Depletion of SIRT7 in cultured colorectal cancer cells induced radiosensitivity triggering cell death. 28435470 2017
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.030 Biomarker disease BEFREE Sirt7 knockdown significantly inhibited colorectal cancer cell proliferation, colony formation, and motility. 24771643 2014