SIRT6, sirtuin 6, 51548

N. diseases: 195; N. variants: 2
Disease: Sepsis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0243026
Disease: Sepsis
Sepsis 		0.040 Biomarker disease BEFREE We showed recently that SIRT6 oxidation during hyper-inflammation of sepsis modulates its glycolytic function. 30203196 2019
CUI: C0243026
Disease: Sepsis
Sepsis 		0.040 Biomarker disease BEFREE The aim of this study was to investigate the mechanism through which SIRT6 relieved acute kidney injury (AKI) caused by sepsis. 30700227 2019
CUI: C0243026
Disease: Sepsis
Sepsis 		0.040 Biomarker disease BEFREE Sulfenylation of SIRT6 occurs in THP1 cells and primary human promonocytes during inflammation and in splenocytes from mice with sepsis. 28887543 2017
CUI: C0243026
Disease: Sepsis
Sepsis 		0.040 Biomarker disease BEFREE We reported that NAD(+)-dependent SIRT1, RELB, and SIRT6 nuclear proteins in monocytes regulate a switch from the glycolysis-dependent acute inflammatory response to fatty acid oxidation-dependent sepsis adaptation. 25404738 2015