Disease: Primary Myelofibrosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		0.030 Biomarker disease BEFREE Platelet-derived growth factor receptor β activation and regulation in murine myelofibrosis. 31672904 2019
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		0.030 Biomarker disease BEFREE BCR-ABL1-positive or PDGFRB-rearranged) and also assist in specific treatment selection (e.g. lenalidomide therapy is active in MF associated with del(5q). 19141119 2009
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		0.030 Biomarker disease BEFREE Other mutations of putative pathogenetic relevance in MPDs include: JAK2V617F in PV, ET, and PMF; JAK2 exon 12 mutations in PV; MPLW515L/K in PMF and ET; KITD816V in SM; FIP1L1-PDGFRA in CEL-SM; rearrangements of PDGFRB in CEL-CMML and FGFR1 in stem cell leukemia-lymphoma syndrome; and RAS/PTPN11/NF1 mutations in JMML. 17351342 2007