Disease: Neurilemmoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027809
Disease: Neurilemmoma
Neurilemmoma 		0.050 AlteredExpression disease BEFREE Schwannomas expressed higher levels of platelet-derived growth factor receptor-β (2.1) than malignant peripheral nerve sheath tumors (MPNSTs) (1.5, p = 0.004) and neurofibromas (1.33, p = 0.007). 28885122 2018
CUI: C0027809
Disease: Neurilemmoma
Neurilemmoma 		0.050 Biomarker disease BEFREE Schwannoma basal proliferation is, however, only partly dependent on PDGFR-β and is completely independent of ErbB2/3. 22821509 2012
CUI: C0027809
Disease: Neurilemmoma
Neurilemmoma 		0.050 AlteredExpression disease BEFREE The PDGFR and c-Raf inhibitor sorafenib (BAY 43-9006; Bayer Pharmaceuticals), currently approved for treatment of advanced renal cell cancer, inhibits both basal and PDGFRbeta-mediated ERK1/2 and AKT activity and decreases cell proliferation in human schwannoma cells, suggesting that this drug constitutes a promising tool to treat schwannomas. 18593924 2008
CUI: C0027809
Disease: Neurilemmoma
Neurilemmoma 		0.050 AlteredExpression disease BEFREE Expressions of PDGF-BB and EGF receptors (PDGFR-beta and EGFR) mRNAs were detected more frequently and their proteins were expressed at higher levels in MPNST tissues than benign peripheral nerve sheath tumors (schwannomas and neurofibromas). 17558420 2007
CUI: C0027809
Disease: Neurilemmoma
Neurilemmoma 		0.050 Biomarker disease LHGDN Overexpression of the NF2 gene inhibits schwannoma cell proliferation through promoting PDGFR degradation. 14612918 2003