SF3B6, splicing factor 3b subunit 6, 51639

N. diseases: 116; N. variants: 0
Disease: Retinopathy of Prematurity ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0035344
Disease: Retinopathy of Prematurity
Retinopathy of Prematurity 		0.030 Biomarker disease BEFREE Aggressive angiogenesis, tortuous arteries and enlarged veins were observed in the retinal vasculature of KRN633-treated (ROP) rats from P14 to P28, compared to age-matched control (vehicle-treated) animals. 31788758 2020
CUI: C0035344
Disease: Retinopathy of Prematurity
Retinopathy of Prematurity 		0.030 AlteredExpression disease BEFREE Retinal vasodilator responses were assessed on P35 by measuring the diameter of retinal arterioles in fundus images.<b>Results</b>: In retinas of KRN633-treated (ROP) rats, progressive angiogenesis, tortuous arteries, enlarged veins, and enhanced expression of α-smooth muscle actin in pericytes on capillaries and veins were observed on P14. 31317786 2019
CUI: C0035344
Disease: Retinopathy of Prematurity
Retinopathy of Prematurity 		0.030 AlteredExpression disease BEFREE Therefore, VEGF and PEDF expression was determined in the ROP model and in RA-raised rat pups at P14 and P18. 21738387 2011