SERPINF1, serpin family F member 1, 5176

N. diseases: 294; N. variants: 15
Disease: Glycogen storage disease type II ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017921
Disease: Glycogen storage disease type II
Glycogen storage disease type II 		0.040 Biomarker disease BEFREE Here, we will discuss the important role of thrombospondins and pigment epithelium-derived factor, two major endogenous inhibitors of angiogenesis, in retinal and choroidal vascular homeostasis and their potential alterations during AMD and choroidal neovascularization (CNV). 28679845 2017
CUI: C0017921
Disease: Glycogen storage disease type II
Glycogen storage disease type II 		0.040 Biomarker disease BEFREE Further studies of comprehensive PEDF gene variations are required to characterize the susceptibility of PEDF gene in the pathogenesis of AMD. 21174599 2011
CUI: C0017921
Disease: Glycogen storage disease type II
Glycogen storage disease type II 		0.040 GeneticVariation disease BEFREE The aim of this study was to validate the previously reported association of the PEDF Met72Thr variant in a well characterized Japanese population with neovascular AMD and PCV. 19503741 2009
CUI: C0017921
Disease: Glycogen storage disease type II
Glycogen storage disease type II 		0.040 Biomarker disease BEFREE The primary objectives of this investigation are: (1) to assess the safety, tolerability and feasibility of intravitreal injection of Ad(GV)PEDF.11D in patients with severe, neovascular AMD, (2) to identify the maximum tolerated dose (MTD) of Ad(GV)PEDF.11D, and (3) to get some indication of potential activity of Ad(GV)PEDF.11D. 11727737 2001