PGR, progesterone receptor, 5241

N. diseases: 392; N. variants: 33
Disease: Diabetes Mellitus, Non-Insulin-Dependent ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.030 Biomarker disease BEFREE Multivariable ordinal logistic regression was used to investigate the association between T2D/insulin and breast cancer characteristics, including TNM classification (tumor size, lymph node status, metastasis), morphology, grade, estrogen receptor and progesterone receptor (PR), human epidermal growth factor receptor 2, and molecular subtype. 30679303 2019
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.030 Biomarker disease BEFREE We conducted a retrospective multi-center population-based case-case study consisting of 4,557 breast cancer cases to evaluate the impact of type II diabetes and diabetes medications on the risk of different breast cancer molecular subtypes [ER<sup>+</sup>/HER2<sup>-</sup>, ER<sup>+</sup>/HER2<sup>+</sup>, triple negative (ER<sup>-</sup>/PR<sup>-</sup>/HER2<sup>-</sup>), and HER2 overexpressing (H2E, ER<sup>-</sup>/PR<sup>-</sup>/HER2<sup>+</sup>)]. 31395589 2019
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.030 Biomarker disease BEFREE Nevertheless, the PGR SNPs-T2DM association was not statistically significant in other ethnic populations. 29417738 2018