PGR, progesterone receptor, 5241

N. diseases: 392; N. variants: 33
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.320 Biomarker disease BEFREE Immunohistochemical staining for progesterone receptor isoform B (PR-B) and nuclear factor kappa B (NFκB) was done with the fixed tissue blocks of their endometriomas which were collected at the time of surgery. 27452080 2017
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.320 AlteredExpression disease BEFREE The objective of this study was to determine whether the increased AKT or MAPK kinase-1/2 (MEK1/2) activity observed in endometriotic stromal cells (OSIS) from ovarian endometriomas influences levels of PR protein. 24064688 2013
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.320 Biomarker disease CTD_human Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis. 21232532 2011
CUI: C0269102
Disease: Endometrioma
Endometrioma
0.320 Biomarker disease CTD_human Unique transcriptome, pathways, and networks in the human endometrial fibroblast response to progesterone in endometriosis. 20864642 2011