Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0079772
Disease: T-Cell Lymphoma
T-Cell Lymphoma
0.060 AlteredExpression disease BEFREE Cytotoxic and antiproliferative effects of the 1C compound were assessed by thiazolyl blue tetrazolium bromide (MTT) method in mouse T-cell lymphoma and human colon adenocarcinoma cells expressing ABCB1. 31810914 2019
CUI: C0079772
Disease: T-Cell Lymphoma
T-Cell Lymphoma
0.060 AlteredExpression disease BEFREE These results indicate that treatment with a ROS scavenger is a potential therapeutic strategy to overcome resistance to anti-cancer drugs by downregulating the expression of P-gp in EBV-positive NK/T-cell lymphoma. 30972167 2019
CUI: C0079772
Disease: T-Cell Lymphoma
T-Cell Lymphoma
0.060 AlteredExpression disease BEFREE Collectively, our results demonstrate that PIM1 overexpression in TCLs participates in cancer cell protection from apoptosis and leads to doxorubicin resistance by inducing c-myc expression, indicating that PIM1 may be a promising target in TCL treatment. 30020405 2018
CUI: C0079772
Disease: T-Cell Lymphoma
T-Cell Lymphoma
0.060 Biomarker disease BEFREE Effect of compound 1 on the reversion of multidrug resistant (MDR) mediated by Pglycoprotein (P-gp) against cancer cells was evaluated with a rhodamine-123 exclusion screening test on human mdr1 gene transfected mouse gene transfected L5178 and L5178Y mouse T-cell lymphoma. 28606042 2017
CUI: C0079772
Disease: T-Cell Lymphoma
T-Cell Lymphoma
0.060 AlteredExpression disease LHGDN Our results suggest that P-gp expression is related with poor treatment outcomes of extranodal NK/T-cell lymphoma, nasal type. 18756548 2008
CUI: C0079772
Disease: T-Cell Lymphoma
T-Cell Lymphoma
0.060 AlteredExpression disease BEFREE We measured tumoral CYP3A and MDR1 mRNA content in 44 T-cell lymphomas, finding a large variation in CYP3A expression. 17634410 2007