Disease: Acute Coronary Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome 		0.070 GeneticVariation disease BEFREE Distribution of polymorphisms in the CYP2C19 and ABCB1 genes among patients with acute coronary syndrome in Lower Silesian population. 31778598 2019
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome 		0.070 GeneticVariation disease BEFREE The aim of this pilot prospective study was to evaluate 12-month cardiovascular outcomes in elderly patients with acute coronary syndrome (ACS) receiving dual antiplatelet therapy (aspirin and clopidogrel) according to the clustering of CYP2C19 and ABCB1 genetic variants. 29936693 2018
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome 		0.070 GeneticVariation disease BEFREE Genetic polymorphisms of CYP2C19 2 and ABCB1 C3435T affect the pharmacokinetic and pharmacodynamic responses to clopidogrel in 401 patients with acute coronary syndrome. 25542807 2015
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome 		0.070 Biomarker disease BEFREE We sought to assess the relationships between platelet reactivity at different time points, CYP2C19*2 and ABCB1 status and clinical outcomes in patients with acute coronary syndromes (ACS). 23148794 2013
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome 		0.070 Biomarker disease BEFREE We genotyped ABCB1 in 2932 patients with acute coronary syndromes undergoing percutaneous intervention who were treated with clopidogrel (n=1471) or prasugrel (n=1461) in the TRITON-TIMI 38 trial. 20801494 2010
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome 		0.070 GeneticVariation disease BEFREE Ticagrelor is a more efficacious treatment for acute coronary syndromes than is clopidogrel, irrespective of CYP2C19 and ABCB1 polymorphisms. 20801498 2010
CUI: C0948089
Disease: Acute Coronary Syndrome
Acute Coronary Syndrome 		0.070 GeneticVariation disease BEFREE The C3435T polymorphism of the MDR-1 gene influences ADP dependent platelet reactivity in patients with acute coronary syndrome but does not affect mid-term prognosis in this population. 19784880 2009