SERPINA1, serpin family A member 1, 5265

N. diseases: 482; N. variants: 61
Disease: Pneumonia, Bacterial ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004626
Disease: Pneumonia, Bacterial
Pneumonia, Bacterial 		0.010 Biomarker group BEFREE When administered as intravenous supplementation, the acute phase-reactant alpha-1 antitrypsin (A1AT) reduces the severity of COPD exacerbations in A1AT deficient (AATD) individuals and of bacterial pneumonia in murine models, but the effect of A1AT on AM scavenging functions has not been reported. 28448535 2017