SERPINA1, serpin family A member 1, 5265

N. diseases: 482; N. variants: 61
Disease: Lung Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.320 Biomarker group BEFREE Overall, our results suggest that neutrophil elastase and α1-antitrypsin play important roles in modulating lung tumor proliferation in inflammatory microenvironment and curcumin inhibits neutrophil elastase-induced tumor proliferation via upregulating α1-antitrypsin expression in vitro and in vivo. 22507634 2012
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.320 Biomarker group LHGDN Alpha1-antitrypsin deficiency carriers, tobacco smoke, chronic obstructive pulmonary disease, and lung cancer risk. 18504338 2008
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.320 Biomarker group CTD_human Notably, we demonstrate significant regulation of alpha-1-antitrypsin, alpha-2-macroglobulin, hemoglobin subunit alpha, vitamin D-binding protein, major urinary proteins, and transthyretin (up to eight-fold) in serum of lung tumor bearing mice. 17902193 2007