SERPINB5, serpin family B member 5, 5268

N. diseases: 87; N. variants: 5
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
0.040 PosttranslationalModification disease BEFREE To elucidate the role of the Maspin gene in thyroid cancer, we studied methylation status in the promoter region and its expression in six human undifferentiated thyroid cancer cell lines and in specimens from 92 primary thyroid tumors, consisting of six follicular adenomas, 56 well-differentiated thyroid cancers (WDTCs), 17 poorly differentiated thyroid cancers (PDTCs) and 13 undifferentiated thyroid cancers (UDTCs). 14743202 2004
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
0.040 AlteredExpression disease LHGDN Maspin expression is directly associated with biological aggressiveness of thyroid carcinoma. 15009909 2004
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
0.040 AlteredExpression disease LHGDN Proteome analysis identified maspin as a special feature of papillary thyroid carcinoma. 14532972 2003
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
0.040 PosttranslationalModification disease BEFREE Silencing of the maspin gene by promoter hypermethylation in thyroid cancer. 12964023 2003