SERPINB5, serpin family B member 5, 5268

N. diseases: 87; N. variants: 5
Disease: Primary malignant neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.070 AlteredExpression group BEFREE Further significant negative correlation (Pearson's coefficient [r] = -0.617; P < 0.0001) was observed between MASPIN expression and survival of cancer patients after surgery. 30740890 2019
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.070 Biomarker group BEFREE In addition, serpin B5 and calretinin appear to be candidate biomarkers that may be accessible in patients for monitoring of cancer therapy with ease. 23151231 2013
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.070 Biomarker group BEFREE Apart from SERPINB2 and SERPINB5, the roles of the remaining 13 members of the human SERPINB family in cancer metastasis are still unknown. 21993616 2012
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.070 Biomarker group BEFREE However, MASPIN protein was 6 times more likely to be detected in cancer specimens that harbor a p53 mutation relative to cancer specimens with a wt p53 gene. 21903246 2011
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.070 AlteredExpression group BEFREE The expression pattern of the maspin gene differs among cancer types and normal tissue however, and its significance as a tumor suppressor has been questioned. 15086568 2004
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.070 AlteredExpression group BEFREE The loss of maspin gene expression with increasing malignancy is by transcriptional regulation. 12425757 2002
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.070 AlteredExpression group BEFREE Maspin gene expression is decreased with malignancy and is lost in metastatic cells. 9040939 1997