Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia
0.050 AlteredExpression disease BEFREE Tanshinone IIA induces apoptosis and autophagy in acute monocytic leukemia via downregulation of PI3K/Akt pathway. 31217869 2019
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia
0.050 Biomarker disease BEFREE Dueling for dual inhibition: Means to enhance effectiveness of PI3K/Akt/mTOR inhibitors in AML. 29276026 2018
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia
0.050 Biomarker disease BEFREE Cotargeting BCL-2 and PI3K Induces BAX-Dependent Mitochondrial Apoptosis in AML Cells. 29559471 2018
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia
0.050 AlteredExpression disease BEFREE Constitutive activation of the PI3K/AKT signaling pathway is found in ~50-70% of AML patients. 29143813 2017
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia
0.050 AlteredExpression disease BEFREE Aberrant activation of the PI3K/mTOR pathway promotes resistance to sorafenib in AML. 26999641 2016