Disease: Influenza A ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2062441
Disease: Influenza A
Influenza A 		0.060 Biomarker disease BEFREE The phosphorylation of IGF1 receptor triggered the PI3K/AKT and MAPK signaling pathways to induce an inflammatory response after IAV infection. 31849847 2019
CUI: C2062441
Disease: Influenza A
Influenza A 		0.060 Biomarker disease BEFREE Notably, ameliorated p85β-binding is insufficient for bat FLUAV NS1 to activate PI3K, and a chimeric bat FLUAV expressing NS1 with engineered hydrophobic patch mutations exhibits cell-type-dependent, but species-independent, propagation phenotypes. 29237829 2018
CUI: C2062441
Disease: Influenza A
Influenza A 		0.060 Biomarker disease BEFREE These findings highlight novel biphasic roles of FAK activation during IAV infection and indicate that FAK serves as a central link between receptor-mediated PI3K activation and actin reorganization during IAV infection. 24696469 2014
CUI: C2062441
Disease: Influenza A
Influenza A 		0.060 Biomarker disease BEFREE This novel mechanism of Dlg1 subversion by adenovirus to dysregulate PI3K could be used by other pathogenic viruses, such as human papillomavirus, human T-cell leukemia virus type 1, and influenza A virus, which also target Dlg1 and activate PI3K in cells. 24788832 2014
CUI: C2062441
Disease: Influenza A
Influenza A 		0.060 Biomarker disease BEFREE Here we show that accumulation of vRNA in cells infected with influenza A or B viruses results in PI3K activation. 21899695 2011
CUI: C2062441
Disease: Influenza A
Influenza A 		0.060 Biomarker disease BEFREE Phosphatidylinositol 3-kinase (PI3K)/Akt signalling pathway can support the replication of influenza A virus through binding of viral NS1 protein to the Src homology 3 (SH3) domain of p85beta regulatory subunit of PI3K. 20653952 2010