Disease: Primary differentiated carcinoma of thyroid gland ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4722172
Disease: Primary differentiated carcinoma of thyroid gland
Primary differentiated carcinoma of thyroid gland 		0.030 Biomarker disease BEFREE Genetic alterations in pathways, including the mitogen‑activated protein kinase (MAPK)/extracellular signal‑regulated kinase (Erk) and phosphatidylinositol‑3‑kinase (PI3K)/protein kinase B (Akt) pathways, are the driving force behind the development of differentiated thyroid cancer cases into aggressive and undifferentiated forms of thyroid cancer. 30365150 2019
CUI: C4722172
Disease: Primary differentiated carcinoma of thyroid gland
Primary differentiated carcinoma of thyroid gland 		0.030 GeneticVariation disease BEFREE We found 3.37% and 2.45% (includes Q214H, a novel <i>PTEN</i> mutation) in GPCR-mediated PI3K pathway of pediatric and adult DTCs, respectively. 31289610 2019
CUI: C4722172
Disease: Primary differentiated carcinoma of thyroid gland
Primary differentiated carcinoma of thyroid gland 		0.030 Biomarker disease BEFREE PI3K inhibitors have the potential to increase radioiodide accumulation in some differentiated thyroid cancer. 18762555 2008