Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0432283
Disease: Osteoglophonic dwarfism
Osteoglophonic dwarfism
0.050 Biomarker disease BEFREE Further more, treatment with LY294002 (specific PI3K inhibitor), PD98059 (specific ERK inhibitor), brusatol (specific Nrf2 inhibitor) and SnPP (specific HO-1 inhibitor) deprived almost all the effects of QMA in MCAO rats and OGD-treated PC12 cells. 30550742 2019
CUI: C0432283
Disease: Osteoglophonic dwarfism
Osteoglophonic dwarfism
0.050 Biomarker disease BEFREE Human amniotic epithelial cells (HAECs) were treated with ligustrazine (1, 10, 100 μM) and PI3K inhibitor wortmannin (100 μM), following oxygen-glucose deprivation (OGD) treatment. 31250662 2019
CUI: C0432283
Disease: Osteoglophonic dwarfism
Osteoglophonic dwarfism
0.050 Biomarker disease BEFREE However, it was revealed that PI3K inhibitor, LY294002, could attenuate the effects of TSLP on in vitro angiogenesis of OGD‑treated HUVECs. 29257253 2018
CUI: C0432283
Disease: Osteoglophonic dwarfism
Osteoglophonic dwarfism
0.050 AlteredExpression disease BEFREE Furthermore, the results suggest that activation of PI3k/Akt/GSK-3β signaling pathway serves a role in attenuating OGD injury. 30186461 2018
CUI: C0432283
Disease: Osteoglophonic dwarfism
Osteoglophonic dwarfism
0.050 Biomarker disease BEFREE These results indicate that apoptosis of astrocytes induced by OGD injury is associated with the MAPK and PI3k/Akt pathways. 27601172 2017