Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0679403
Disease: Vascular stenosis
Vascular stenosis
0.010 Biomarker disease BEFREE Our data showed that p110δ PI3K plays a main role in promoting neointimal thickening and inflammatory processes during vascular stenosis, with its inhibition providing significant reduction in restenosis following carotid injury. p110δ-selective inhibitors, recently approved for the treatment of human B-cell malignancies, therefore, present a new therapeutic opportunity to prevent the restenosis upon artery injury. 28851839 2017