|
Cerebral Infarction
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The protective effect of lncRNA SNHG1 on the rats with cerebral infarction is correlated with the activation of the PI3K/Akt signaling pathway.
|
31298389 |
2019 |
|
Cerebral Infarction
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Besides, the inhibition of PI3K/AKT decreased Bmal1 expression and the effect of melatonin on Bmal1 after both OGD in vitro and focal cerebral ischemia in vivo.
|
31836786 |
2019 |
|
Cerebral Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
To study the effect of promethazine on neuronal apoptosis in rats with cerebral infarction (CI) through the phosphatidylinositol 3-hydroxy kinase/protein kinase B (PI3K/Akt) signaling pathway.
|
31389591 |
2019 |
|
Cerebral Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
However, treatment with atorvastatin after cerebral infarction can effectively rejuvenate NSCs through activating the PI3K and ERK pathways to aid in brain regeneration.
|
30073508 |
2019 |
|
Cerebral Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
Our findings suggest that the PI3K/Akt-dependent GSK-3β signaling pathway was involved in the proliferation of neural progenitor cells under a pathologic condition, such as hypoxia and/or cerebral ischemia in vivo.
|
29981053 |
2019 |
|
Cerebral Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
Neuroprotective effect of ginkgetin in experimental cerebral ischemia/reperfusion via apoptosis inhibition and PI3K/Akt/mTOR signaling pathway activation.
|
31265179 |
2019 |
|
Cerebral Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
In conclusion, the data obtained demonstrated the possible future use of miRNA‑634 as a therapeutic target in cerebral infarction through the PI3K/Akt pathway.
|
30015915 |
2018 |
|
Cerebral Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
MiRNA-26a promotes angiogenesis in a rat model of cerebral infarction via PI3K/AKT and MAPK/ERK pathway.
|
29917203 |
2018 |
|
Cerebral Infarction
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Resveratrol attenuates brain damage in permanent focal cerebral ischemia via activation of PI3K/Akt signaling pathway in rats.
|
30156477 |
2018 |
|
Cerebral Infarction
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Intranasal administration of nerve growth factor promotes angiogenesis via activation of PI3K/Akt signaling following cerebral infarction in rats.
|
30662601 |
2018 |
|
Cerebral Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
Icariin and mesenchymal stem cells synergistically promote angiogenesis and neurogenesis after cerebral ischemia via PI3K and ERK1/2 pathways.
|
30245466 |
2018 |
|
Cerebral Infarction
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Our data suggest that Apelin-13 protects BBB from disruption after cerebral ischemia both morphologically and functionally, which is highly associated with the increased levels of AQP4, possibly through the activation of ERK and PI3K/Akt pathways.
|
28402976 |
2017 |
|
Cerebral Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
Salidroside Inhibits Inflammation Through PI3K/Akt/HIF Signaling After Focal Cerebral Ischemia in Rats.
|
28478514 |
2017 |
|
Cerebral Infarction
|
0.100 |
Biomarker
|
disease |
BEFREE |
The bone marrow mononuclear cells reduce the oxidative stress of cerebral infarction through PI3K/AKT/NRF2 signaling pathway.
|
29272009 |
2017 |
|
Cerebral Infarction
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Particular phosphorylation of PI3K/Akt on Thr308 via PDK-1 and PTEN mediates melatonin's neuroprotective activity after focal cerebral ischemia in mice.
|
28395173 |
2017 |
|
Cerebral Infarction
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
We constructed a reporter plasmid to detect PI3K p55γ promoter activity and found that berberine enhanced PI3K p55γ promoter activity during cerebral ischemia-reperfusion.
|
22119079 |
2012 |