PLA2G1B, phospholipase A2 group IB, 5319

N. diseases: 268; N. variants: 2
Disease: Neuroblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma 		0.050 AlteredExpression disease BEFREE Taiwan cobra phospholipase A2 elicits posttranscriptional up-regulation of ADAM17 in human neuroblastoma SK-N-SH cells. 20506406 2010
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma 		0.050 Biomarker disease BEFREE The aim of the present study is to elucidate the signaling pathway involved in death of human neuroblastoma SK-N-SH cells induced by Naja naja atra phospholipase A(2) (PLA(2)). 19009558 2009
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma 		0.050 Biomarker disease BEFREE Compound 24, an alkyl-substituted amino acid amide, previously found to activate pertussis toxin-sensitive G proteins in cell membranes and membrane protein fractions, was used as a tool to determine the mechanism/location of nicotine inhibition of amyloid beta peptide-stimulated phospholipase A2 and D activities in a human neuroblastoma cell line, LA-N-2, in vitro. 12515313 2002
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma 		0.050 GeneticVariation disease BEFREE Lack of phospholipase A2 mutations in neuroblastoma, melanoma and colon-cancer cell lines. 9219842 1997
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma 		0.050 GeneticVariation disease BEFREE We analyzed 19 neuroblastomas to detect point mutations of the PLA2S-II gene by PCR-single strand conformational polymorphism (SSCP). 9022130 1997