PLA2G4A, phospholipase A2 group IVA, 5321

N. diseases: 202; N. variants: 15
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0151650
Disease: Renal fibrosis
Renal fibrosis
0.020 AlteredExpression disease BEFREE In contrast, Ad-cPLA2α DNA, but not its control Ad-GFP DNA in cPLA2α-/- mice, restored the expression of cPLA2α, and Ang II-induced increase in cPLA2 activity and oxidative stress in the SFO, BP, cardiac, and renal fibrosis. 29342227 2018
CUI: C0151650
Disease: Renal fibrosis
Renal fibrosis
0.020 Biomarker disease BEFREE We aimed to determine the role of cPLA2α in bone marrow-derived cells in a murine model of renal fibrosis, unilateral ureteral obstruction (UUO). 29229740 2018