PLAT, plasminogen activator, tissue type, 5327

N. diseases: 392; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity
0.020 Biomarker disease BEFREE With the growth of obesity in the United States and the lack of data supporting dose capping of alteplase, it remains unclear if this dosing practice should continue to be accepted without question. 28129994 2017
CUI: C0028754
Disease: Obesity
Obesity
0.020 AlteredExpression disease BEFREE Leptin is elevated in obesity and studies have shown a positive correlation between leptin and PAI-1 levels in human subjects, along with a negative correlation with tissue-type plasminogen activator (tPA). 20051227 2010