PLAT, plasminogen activator, tissue type, 5327

N. diseases: 392; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0243026
Disease: Sepsis
Sepsis
0.230 Biomarker disease BEFREE Moreover, the inhibitory roles of CKIP-1 in LPS-mediated sepsis and TPA-mediated cutaneous provide a new target for treatments of acute inflammation. 28212865 2017
CUI: C0243026
Disease: Sepsis
Sepsis
0.230 AlteredExpression disease LHGDN Transgenic tissue-type plasminogen activator expression improves host defense during Klebsiella pneumonia. 18194423 2008
CUI: C0243026
Disease: Sepsis
Sepsis
0.230 Therapeutic disease RGD Anti-c5a ameliorates coagulation/fibrinolytic protein changes in a rat model of sepsis. 12000738 2002
CUI: C0243026
Disease: Sepsis
Sepsis
0.230 AlteredExpression disease BEFREE Impaired fibrinolysis, resulting from increased plasminogen activator inhibitor-1 (PAI-1) or reduced tissue-type plasminogen activator (t-PA) plasma levels, may predispose the individual to subacute thrombosis in sepsis and inflammation. 9269770 1997