PLCG1, phospholipase C gamma 1, 5335

N. diseases: 116; N. variants: 7
Disease: Degenerative polyarthritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.020 Biomarker disease BEFREE Consequently, the data reveal that the inhibition of PLCγ1 may provide an attractive therapeutic target for OA therapy, implicating its binding to Akt. 29435116 2018
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.020 AlteredExpression disease BEFREE Interestingly, activated ERK had no inhibitory effect on MMP-13 expression in PLCγ1-transformed OA chondrocytes. 26247939 2015