SHC3, SHC adaptor protein 3, 53358

N. diseases: 72; N. variants: 10
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4086165
Disease: Childhood Neuroblastoma
Childhood Neuroblastoma
0.020 Biomarker disease BEFREE Furthermore, using SKNMC cells stably expressing RAI, we defined a role of RAI in NB cell responses to hypoxia. 29057481 2018
CUI: C4086165
Disease: Childhood Neuroblastoma
Childhood Neuroblastoma
0.020 AlteredExpression disease BEFREE In this study, we analysed the expression levels of ShcA and ShcC proteins in 46 neuroblastoma samples and showed that a significantly higher level of ShcC protein is observed in neuroblastomas with poor prognostic factors such as advanced stage and MYCN amplification (P<0.005), whereas the expression level of ShcA showed no significant association with these factors. 18997821 2009