TPCN1, two pore segment channel 1, 53373

N. diseases: 26; N. variants: 1
Disease: Virus Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0042769
Disease: Virus Diseases
Virus Diseases 		0.010 Biomarker group BEFREE Mammalian two-pore-channels (TPC1, 2; <i>TPCN1, TPCN2</i>) are ubiquitously- expressed, PI(3,5)P<sub>2</sub>-activated, Na<sup>+</sup>-selective channels in the endosomes and lysosomes that regulate luminal pH homeostasis, membrane trafficking, and <i>Ebola</i> viral infection. 31825310 2019