PLIN1, perilipin 1, 5346

N. diseases: 85; N. variants: 9
Disease: Metabolic Syndrome X ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		0.040 AlteredExpression disease BEFREE Perilipin is almost exclusively expressed in white adipocytes, so the serious metabolic sequelae observed in these patients suggest that primary defects in adipose tissue can lead to all the typical features seen in patients with the metabolic syndrome. 23392103 2013
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		0.040 Biomarker disease BEFREE Several perilipin (PLIN) polymorphic sites have been studied for their potential use as markers for obesity and the metabolic syndrome. 18326614 2008
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		0.040 GeneticVariation disease BEFREE Effects of perilipin (PLIN) gene variation on metabolic syndrome risk and weight loss in obese children and adolescents. 18812483 2008
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		0.040 Biomarker disease BEFREE These findings support an important role for PLIN as a candidate gene for obesity risk in humans as well as a modulator of dietary response to therapies aimed to reduce body weight and decrease metabolic syndrome risk. 17353663 2007