TLR9, toll like receptor 9, 54106
N. diseases: 457; N. variants: 11
Source: ALL
Disease | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year |
---|---|---|---|---|---|---|---|
|
0.030 | Biomarker | disease | BEFREE | Pathogenic Helicobacter pylori strains translocate DNA and activate TLR9 via the cancer-associated cag type IV secretion system. | 27157617 | 2016 |
|
0.030 | GeneticVariation | disease | BEFREE | Increase in NF-kappaB binding affinity of the variant C allele of the toll-like receptor 9 -1237T/C polymorphism is associated with Helicobacter pylori-induced gastric disease. | 20038537 | 2010 |
|
0.030 | GeneticVariation | disease | BEFREE | The CD14-159C/T and the TLR9-1237T/C promoter polymorphisms have previously been shown to be associated with various inflammatory conditions including Helicobacter pylori-induced gastritis in Caucasian populations. | 19337058 | 2009 |