TLR9, toll like receptor 9, 54106

N. diseases: 457; N. variants: 11
Disease: Carcinoma of lung ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.070 Biomarker disease BEFREE Preclinical development of the TLR9 agonist DV281 as an inhaled aerosolized immunotherapeutic for lung cancer: Pharmacological profile in mice, non-human primates, and human primary cells. 30502651 2019
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.070 Biomarker disease BEFREE Our findings may identify the role that TLR9 and mtDNA play in lung cancer progression and metastasis. 30431116 2019
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.070 AlteredExpression disease BEFREE Our results suggest that TLR9 expression in mononuclear cells was associated with an angiogenic phenotype and promoted lung cancer progression. 23913633 2014
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.070 AlteredExpression disease BEFREE The expression of TLR9 and miR-26a in lung cancer tissues obtained from lung cancer patients was increased. 24788552 2014
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.070 Biomarker disease BEFREE Our previous study demonstrated that the TLR9 agonist CpG ODNs could significantly enhance the progression of human lung cancer cells in vivo. 19854217 2010
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.070 AlteredExpression disease BEFREE We found that both mRNA and protein levels of TLR4 and TLR9 were strongly expressed in lung cancer tissue. 18763053 2009
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.070 Biomarker disease BEFREE CXCR4/SDF-1 pathway is crucial for TLR9 agonist enhanced metastasis of human lung cancer cell. 19302975 2009