TLR9, toll like receptor 9, 54106

N. diseases: 457; N. variants: 11
Disease: HIV-1 infection ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.040 Biomarker disease BEFREE TLR9 Enhancement of antiviral immunity in chronic HIV-1 infection: a phase 1B/2A trial; ClinicalTrials.gov NCT02443935. 30932955 2019
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.040 Biomarker disease BEFREE Our data reveal that opiate use plays a cofactor role in pathogenesis of HIV-1 infection through inhibition of TLR9 pathway. 29026137 2017
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.040 GeneticVariation disease BEFREE Overall, results demonstrate a significant correlation between specific genetic variants of the TLR9 gene and risk of MTCT of HIV-1, thus confirming a critical role of innate immunity in perinatal HIV-1 infection. 20500814 2010
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.040 GeneticVariation disease BEFREE Rapid progression of HIV-1 infection was associated with TLR9 polymorphisms. 17301562 2007