TLR9, toll like receptor 9, 54106

N. diseases: 457; N. variants: 11
Disease: Immunosuppression ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4048329
Disease: Immunosuppression
Immunosuppression 		0.030 AlteredExpression disease BEFREE There is a relationship between sepsis-induced immunosuppression and serum TLR-9 levels. 30348730 2019
CUI: C4048329
Disease: Immunosuppression
Immunosuppression 		0.030 GeneticVariation disease BEFREE There is no relation between sepsis and both TLR-9 (C>T) and TLR-9(-1486 T>C) polymorphisms; however, there is a relation between sepsis and decreased serum TLR-9 levels of both TLR-9 (-1486 T>C) TT and TLR-9 (C>T) TT polymorphisms due to sepsis-associated immunosuppression. 27566084 2017
CUI: C4048329
Disease: Immunosuppression
Immunosuppression 		0.030 Biomarker disease BEFREE Overall, we demonstrate the accumulation of granulocytic MDSCs with prostate cancer progression and the feasibility of using TLR9-targeted STAT3siRNA delivery strategy to alleviate MDSC-mediated immunosuppression. 25967142 2015