GPR88, G protein-coupled receptor 88, 54112

N. diseases: 21; N. variants: 1
Disease: Parkinson Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		0.020 Biomarker disease BEFREE Intact male GPR88 KO mice showed diminished tacrine-induced PD-like tremor and spontaneous hyperlocomotion. 31666199 2020
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		0.020 AlteredExpression disease BEFREE GPR88, a brain-specific oGPCR with particularly robust expression in the striatum, regulates diverse brain and behavioral functions, including cognition, mood, movement control, and reward-based learning, and is thus emerging as a novel drug target for central nervous system disorders including schizophrenia, Parkinson's disease, anxiety, and addiction. 30540906 2019