Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009319
Disease: Colitis
Colitis
0.040 Biomarker disease BEFREE We confirmed that inhibition of TREM-1 attenuates the severity of colitis clinically, endoscopically and histologically. 28961797 2018
CUI: C0009319
Disease: Colitis
Colitis
0.040 Biomarker disease BEFREE Protective effects of guggulsterone against colitis are associated with the suppression of TREM-1 and modulation of macrophages. 29543509 2018
CUI: C0009319
Disease: Colitis
Colitis
0.040 AlteredExpression disease BEFREE Serum sTREM-1 and TREM-1 mRNA expression levels were further determined in sera and colonic tissues collected at various time-points post disease induction in an experimental mouse model of colitis and correlated with disease activity. 22410349 2012
CUI: C0009319
Disease: Colitis
Colitis
0.040 Biomarker disease BEFREE Blocking TREM-1 by the administration of an antagonistic peptide substantially attenuated clinical course and histopathological alterations in experimental mouse models of colitis. 17853946 2007