Disease: Cystic Fibrosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0010674
Disease: Cystic Fibrosis
Cystic Fibrosis 		0.030 Biomarker disease BEFREE Upstream regulator analysis indicated dysregulation of CCL5, NF-κB and IL1A due to CF while dysregulation of TREM1 and TP53 regulators were associated with CF phenotype. 31118097 2019
CUI: C0010674
Disease: Cystic Fibrosis
Cystic Fibrosis 		0.030 AlteredExpression disease BEFREE Cytokine production, TREM-1 expression, and phagocytosis were significantly lower for the healthy volunteer monocytes exposed to CF-09, compared with those exposed to CF-96. 25118167 2015
CUI: C0010674
Disease: Cystic Fibrosis
Cystic Fibrosis 		0.030 AlteredExpression disease LHGDN We conclude that down-regulation of TREM-1 expression in cystic fibrosis patients is at least partly responsible for the endotoxin tolerance state in which their monocytes are locked. 18628981 2008