Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0031090
Disease: Periodontal Diseases
Periodontal Diseases
0.040 Biomarker group BEFREE TREM-1 inhibitors such as LR12 could be interesting for the modulation of the excessive inflammatory response that occurs during periodontal disease. 29779263 2018
CUI: C0031090
Disease: Periodontal Diseases
Periodontal Diseases
0.040 AlteredExpression group BEFREE Longitudinal studies determining TREM-1, sTREM-1, and TREM-2 levels in tissues over time and progression of periodontal diseases would provide valuable information in the role of TREM receptors as indicators of or contributors to the disease process. 29027827 2017
CUI: C0031090
Disease: Periodontal Diseases
Periodontal Diseases
0.040 Biomarker group BEFREE TREM-1 is considered as an amplifier of the immune response, while TREM-2 is a negative regulator that has yet to be explored in periodontal disease before. 27624412 2017
CUI: C0031090
Disease: Periodontal Diseases
Periodontal Diseases
0.040 AlteredExpression group BEFREE In conclusion, this study reveals that TREM-1 tissue expression is enhanced in periodontal disease, and correlates with the level of periodontal pathogens. 24924298 2014