POLB, DNA polymerase beta, 5423

N. diseases: 63; N. variants: 6
Disease: Stomach Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.030 GeneticVariation disease BEFREE We have previously identified a T to C point mutation at nucleotide 889 (T889C) in DNA polymerase beta (POLB) gene, a key enzyme involved in base excision repair in primary GCs. 25561897 2015
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.030 GeneticVariation disease BEFREE The Leu22Pro (L22P) DNA polymerase beta variant was identified in a gastric carcinoma. 18039710 2008
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.030 GeneticVariation disease BEFREE Functional mutation of DNA polymerase beta found in human gastric cancer--inability of the base excision repair in vitro. 10556592 1999