DisGeNET - a database of gene-disease associations

POLD1, DNA polymerase delta 1, catalytic subunit, 5424

N. diseases: 189; N. variants: 9

Disease: Herpes Simplex Infections ×

Source: ALL

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Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Disease

Score _gda

Association Type

Type

Original DB

Sentence supporting the association

PMID

PMID Year

CUI:	C0019348
Disease:	Herpes Simplex Infections

Herpes Simplex Infections

0.020

Biomarker

group

BEFREE

Herpes simplex virus 1 activates cdc2 to recruit topoisomerase II alpha for post-DNA synthesis expression of late genes.

12665617

2003

CUI:	C0019348
Disease:	Herpes Simplex Infections

Herpes Simplex Infections

0.020

AlteredExpression

group

BEFREE

The role of cdc2 in the expression of herpes simplex virus genes.

10995483

2000