Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4049446
Disease: Neointimal hyperplasia
Neointimal hyperplasia
0.020 AlteredExpression disease BEFREE Our findings demonstrate that loss of Spry1 attenuates mitogen-induced VSMC proliferation, and thus injury-induced neointimal hyperplasia likely via insufficient activation of Akt signaling causing decreased cyclinD1 and increased p27<sup>Kip1</sup> and a subsequent decrease in Rb and cdc2 phosphorylation. 29105817 2018
CUI: C4049446
Disease: Neointimal hyperplasia
Neointimal hyperplasia
0.020 Biomarker disease BEFREE Antisense oligonucleotides (ASs) to proliferating cell nuclear antigen (PCNA) and Cdc2 kinase (Cdc2 k) can arrest cell cycle progression and inhibit neointimal hyperplasia. 11082394 2000