POLG, DNA polymerase gamma, catalytic subunit, 5428

N. diseases: 462; N. variants: 173
Disease: Chemical and Drug Induced Liver Injury ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.500 SusceptibilityMutation disease RGD Acute liver failure after valproate exposure in patients with POLG1 mutations and the prognosis after liver transplantation. 25065347 2014
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.500 Biomarker disease CTD_human POLG DNA testing as an emerging standard of care before instituting valproic acid therapy for pediatric seizure disorders. 20138553 2010
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.500 Biomarker disease CTD_human Reversible valproate hepatotoxicity due to mutations in mitochondrial DNA polymerase gamma (POLG1). 18208989 2008