Hypercholesterolemia, Familial
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
PON1 QQ192 genotype showed a significantly higher association with FH (p=0.0002).
|
30044465 |
2019 |
Hypercholesterolemia, Familial
|
0.370 |
AlteredExpression
|
disease |
BEFREE |
Erratum: Decreased serum PON1 arylesterase activity in familial hypercholesterolemia patients with a mutated LDLR gene.
|
31323079 |
2019 |
Hypercholesterolemia, Familial
|
0.370 |
Biomarker
|
disease |
CTD_human |
The effect of statin therapy on plasma high-density lipoprotein cholesterol levels is modified by paraoxonase-1 in patients with familial hypercholesterolaemia.
|
16238680 |
2005 |
Hypercholesterolemia, Familial
|
0.370 |
AlteredExpression
|
disease |
LHGDN |
Variation at the paraoxonase gene locus contributes to carotid arterial wall thickness in subjects with familial hypercholesterolemia.
|
15642273 |
2005 |
Hypercholesterolemia, Familial
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
PON1 genotypes (L55M, Q192R, -107C/T, -162A/G, -824G/A, and -907G/C) were determined in 302 patients with familial hypercholesterolemia.
|
15576850 |
2005 |
Hypercholesterolemia, Familial
|
0.370 |
Biomarker
|
disease |
BEFREE |
The effect of statin therapy on plasma high-density lipoprotein cholesterol levels is modified by paraoxonase-1 in patients with familial hypercholesterolaemia.
|
16238680 |
2005 |
Hypercholesterolemia, Familial
|
0.370 |
Biomarker
|
disease |
CTD_human |
Genetic determinants of plasma HDL-cholesterol levels in familial hypercholesterolemia.
|
16030523 |
2005 |
Hypercholesterolemia, Familial
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
In 187 patients with familial hypercholesterolemia, we studied the seven most common single nucleotide polymorphisms (SNPs) in both the coding and promoter sequences of PON1 (L55M, Q192R, T-107C, C-126G, G-162A, G-824A, and C-907G) in terms of PON1 activity and intima media thickness (IMT) of the carotid arterial wall, a validated surrogate marker for CVD.
|
15642273 |
2005 |
Hypercholesterolemia, Familial
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
In our study we assessed the frequency and genotype distribution of the PON1 and PON2 polymorphisms in 197 patients with familial hypercholesterolemia (FH), to determine the possible association between these mutations and susceptibility for CVD.
|
11257265 |
2001 |
Hypercholesterolemia, Familial
|
0.370 |
Biomarker
|
disease |
BEFREE |
Low PON1 activities have been found in familial hypercholesterolemia (FH) and diabetes mellitus.
|
10978257 |
2000 |