PON1, paraoxonase 1, 5444

N. diseases: 496; N. variants: 29
Disease: Takayasu Arteritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0039263
Disease: Takayasu Arteritis
Takayasu Arteritis 		0.010 AlteredExpression disease BEFREE These results show significantly lower PON1 activity associated with HDL-C in TA patients, this activity could be depending on PON1 genotypes; showing that QR/LM/CT has the lowest hydrolytic activity toward paraoxon meanwhile, PON1(192,55,-108) genetic variations are related with reduced PON1 activities, these could be factors contributing to the development of TA disease. 23628180 2013