RETREG1, reticulophagy regulator 1, 54463

N. diseases: 89; N. variants: 6
Disease: Malignant tumor of colon ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.060 Biomarker disease BEFREE Herein, this study aims to determine the interacting partners of FAM134B for the first time in colon cancer and to explore the precise location of FAM134B in cancer signalling pathways. 29964340 2018
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.060 PosttranslationalModification disease BEFREE Methylation-specific high-resolution melt-curve analysis followed by sequencing was used to identify FAM134B promoter methylation in colorectal adenomas (N = 32), colorectal adenocarcinomas (N = 164), matched adjacent non-neoplastic colorectal mucosae (N = 83) and colon cancer cell lines (N = 4). 29318692 2018
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.060 Biomarker disease BEFREE We found excellent sensitivity and specificity for the analysis of FAM134B protein in a panel of colon cancer cell lines and serum samples. 28273937 2017
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.060 Biomarker disease BEFREE To conclude, expression analysis, in vitro and in vivo indicated that FAM134B acts as a cancer suppressor gene in colon cancer. 27120410 2017
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.060 Biomarker disease BEFREE JK1 (FAM134B) represses cell migration in colon cancer: a functional study of a novel gene. 24927874 2014
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.060 AlteredExpression disease BEFREE JK-1(FAM134B) protein expression was studied in a colon cancer cell line by Western blot and immunocytochemistry. 24973512 2014