TOLLIP, toll interacting protein, 54472

N. diseases: 40; N. variants: 10
Disease: Tuberculosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0041296
Disease: Tuberculosis
Tuberculosis 		0.040 GeneticVariation disease BEFREE Evaluation of TLR2, TLR4, and TOLLIP polymorphisms for their role in tuberculosis susceptibility. 29924447 2018
CUI: C0041296
Disease: Tuberculosis
Tuberculosis 		0.040 Biomarker disease BEFREE To identify functional TOLLIP variants and evaluate the role of TOLLIP variation on innate and adaptive immune responses to mycobacteria and susceptibility to tuberculosis. 28463648 2017
CUI: C0041296
Disease: Tuberculosis
Tuberculosis 		0.040 GeneticVariation disease BEFREE Multiple SNPs in IL4 and TOLLIP were associated with TB (P < 0.05). 25521228 2015
CUI: C0041296
Disease: Tuberculosis
Tuberculosis 		0.040 Biomarker disease BEFREE These data demonstrate that TOLLIP has an anti-inflammatory effect on TLR signaling in humans and that TOLLIP deficiency is associated with an increased risk of tuberculosis. 22778396 2012